Jelnes R, Tønnesen K H
Clin Sci (Lond). 1984 Jul;67(1):89-95. doi: 10.1042/cs0670089.
Twenty-four hour continuous recording of xenon (133Xe) wash-out from the forefoot was performed on patients with normal circulations (n = 10) and on patients with different degrees of arterial insufficiency (n = 36). During day hours the calculated subcutaneous blood flow in the forefoot was on average the same in patients with normal circulations and in patients with different degrees of arterial insufficiency (mean: 2.0 +/- 0.8 ml min-1 100 g-1). During sleep the blood flow nearly doubled in patients with normal circulations; no systematic change was seen in patients with intermittent claudication. In patients with severe ischaemia, i.e. having rest pain, the blood flow decreased by approximately 50%. The changes in local blood flow may be due to changes in local sympathetic tone and to changes in local perfusion pressure.
对循环正常的患者（n = 10）和不同程度动脉供血不足的患者（n = 36）进行了24小时连续记录前足氙（133Xe）清除情况的操作。在白天，循环正常的患者和不同程度动脉供血不足的患者前足计算得出的皮下血流平均相同（平均值：2.0 +/- 0.8 ml min-1 100 g-1）。在睡眠期间，循环正常的患者血流几乎增加一倍；间歇性跛行患者未见系统性变化。在有严重缺血即静息痛的患者中，血流减少约50%。局部血流的变化可能是由于局部交感神经张力的变化和局部灌注压力的变化。
