Berényi I, Hajduczki I S, Böszörményi E
Eur Heart J. 1984 Apr;5(4):289-94. doi: 10.1093/oxfordjournals.eurheartj.a061654.
Comparative analysis of coronary arteriography and exercise ECG recordings of 33 patients with ischaemic heart disease is presented. Linear regression was found between the increase of heart rate (HR) as well as increase of systolic blood pressure-heart rate product (SBP X HR) and the level of ST-segment depression developing during exercise. A significant correlation was established between the slope of the regression line (i.e. 'm' coefficient of y = mx + b) expressing the rate of change of ST-segment depression and the degree of coronary artery disease confirmed by arteriography. The average value of 'm' coefficients differed significantly according to the number of diseased vessels (P less than 0.01-0.001). The ratio of maximal ST depression and maximal HR (STmax/HRmax) measured at the end of the exercise indicated reliably the severity of coronary artery disease and is suggested for everyday practice.
本文对33例缺血性心脏病患者的冠状动脉造影和运动心电图记录进行了对比分析。研究发现，运动期间心率（HR）的增加以及收缩压与心率乘积（SBP×HR）的增加与ST段压低水平之间存在线性回归关系。表达ST段压低变化率的回归线斜率（即y = mx + b中的“m”系数）与冠状动脉造影确诊的冠状动脉疾病程度之间建立了显著相关性。“m”系数的平均值根据病变血管数量的不同而有显著差异（P<0.01 - 0.001）。运动结束时测量的最大ST段压低与最大心率之比（STmax/HRmax）可靠地表明了冠状动脉疾病的严重程度，建议在日常实践中使用。
