Kachalov Iu P
Fiziol Zh SSSR Im I M Sechenova. 1984 Apr;70(4):437-42.
Transmural electrical stimulation evokes a multicomponent response in the enterometasympathetic ganglion, the response consisting of early low-amplitude APs and late single AP or bursts of APs. Some of the neurons developed a high-amplitude antidromic spike following the stimulation. Application of ganglio-blocking agent hexonium (10(-6) g/ml), solutions with high magnesium concentration (up to 10 mM) and high-frequency stimulation (30 Hz) led to disappearance of single APs but not the bursts of APs. This suggests that some components of the response are synaptically evoked in ortho- and antidromic stimulations. The remaining spikes reflect conduction of excitation along continuous nerve fibers. Transmural electrical stimulation leads to either increase or decrease in the spontaneous firing rate of neurons except the cells generating stable burst-like firing. Reasons and significance of these changes are discussed.
透壁电刺激可在肠交感神经节诱发多成分反应，该反应由早期低幅动作电位和晚期单个动作电位或动作电位簇组成。一些神经元在刺激后产生高幅逆向峰电位。应用神经节阻断剂己双铵（10(-6) g/ml）、高镁浓度溶液（高达10 mM）和高频刺激（30 Hz）会导致单个动作电位消失，但动作电位簇不会消失。这表明该反应的某些成分在顺向和逆向刺激中是由突触诱发的。其余的峰电位反映了兴奋沿连续神经纤维的传导。透壁电刺激除了使产生稳定簇状放电的细胞外，会导致神经元的自发放电率增加或降低。讨论了这些变化的原因和意义。
