Pounder D J
Forensic Sci Int. 1984 Jun;25(2):123-31. doi: 10.1016/0379-0738(84)90021-5.
A previously healthy 34-year-old Dutch immigrant to Australia died unexpectedly in his sleep. At autopsy the only significant finding was a floppy aortic valve (FAV). Histologic, histochemical and electron microscopic studies corroborated the macroscopic diagnosis. Previously described associations of the FAV include the floppy mitral valve, Marfan's syndrome, aortic root dilatation and aortic cystic medial necrosis. None of these features were found in the present case which is the first recorded example of isolated FAV presenting as sudden death. The mechanism of death is obscure, and while it is presumed to be dysrhythmic, a detailed histological examination of the cardiac conducting system revealed no anatomic abnormality.
一名先前健康的34岁荷兰裔澳大利亚移民在睡梦中意外死亡。尸检时唯一重要的发现是主动脉瓣松弛（FAV）。组织学、组织化学和电子显微镜研究证实了宏观诊断。先前描述的FAV相关情况包括二尖瓣松弛、马方综合征、主动脉根部扩张和主动脉中层囊性坏死。本病例中未发现这些特征，这是首例有记录的以猝死形式出现的孤立性FAV病例。死亡机制尚不清楚，虽然推测是心律失常，但对心脏传导系统进行的详细组织学检查未发现解剖学异常。
