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介导腐生葡萄球菌凝集绵羊红细胞的寡糖结构。

Oligosaccharide structures mediating agglutination of sheep erythrocytes by Staphylococcus saprophyticus.

作者信息

Gunnarsson A, Mårdh P A, Lundblad A, Svensson S

出版信息

Infect Immun. 1984 Jul;45(1):41-6. doi: 10.1128/iai.45.1.41-46.1984.

Abstract

Agglutination of sheep erythrocytes by Staphylococcus saprophyticus was used as a model system for adherence studies. Glycolipids were isolated from sheep erythrocyte membranes, and oligosaccharides were prepared by trifluoroacetolysis. The oligosaccharides were characterized by sugar analyses, methylation analyses, gas-liquid chromatography-mass spectrometry, and nuclear magnetic resonance spectroscopy. We showed that oligosaccharides containing terminal beta-D-galactose-p-(1-4)-beta-D-2-acetamido-2-deoxyglucose-p-(1- were good inhibitors of the hemagglutination of sheep erythrocytes by S. saprophyticus.

摘要

腐生葡萄球菌对绵羊红细胞的凝集作用被用作黏附研究的模型系统。从绵羊红细胞膜中分离出糖脂,并通过三氟乙酰解制备寡糖。通过糖分析、甲基化分析、气-液色谱-质谱联用和核磁共振光谱对寡糖进行了表征。我们发现,含有末端β-D-半乳糖-p-(1-4)-β-D-2-乙酰氨基-2-脱氧葡萄糖-p-(1-的寡糖是腐生葡萄球菌对绵羊红细胞血凝作用的良好抑制剂。

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本文引用的文献

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Glycolipids isolated from porcine intestine.从猪小肠中分离出的糖脂。
Arch Biochem Biophys. 1968 Sep 20;127(1):140-9. doi: 10.1016/0003-9861(68)90210-5.

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