介导腐生葡萄球菌凝集绵羊红细胞的寡糖结构。
Oligosaccharide structures mediating agglutination of sheep erythrocytes by Staphylococcus saprophyticus.
作者信息
Gunnarsson A, Mårdh P A, Lundblad A, Svensson S
出版信息
Infect Immun. 1984 Jul;45(1):41-6. doi: 10.1128/iai.45.1.41-46.1984.
Abstract
Agglutination of sheep erythrocytes by Staphylococcus saprophyticus was used as a model system for adherence studies. Glycolipids were isolated from sheep erythrocyte membranes, and oligosaccharides were prepared by trifluoroacetolysis. The oligosaccharides were characterized by sugar analyses, methylation analyses, gas-liquid chromatography-mass spectrometry, and nuclear magnetic resonance spectroscopy. We showed that oligosaccharides containing terminal beta-D-galactose-p-(1-4)-beta-D-2-acetamido-2-deoxyglucose-p-(1- were good inhibitors of the hemagglutination of sheep erythrocytes by S. saprophyticus.
摘要
腐生葡萄球菌对绵羊红细胞的凝集作用被用作黏附研究的模型系统。从绵羊红细胞膜中分离出糖脂，并通过三氟乙酰解制备寡糖。通过糖分析、甲基化分析、气-液色谱-质谱联用和核磁共振光谱对寡糖进行了表征。我们发现，含有末端β-D-半乳糖-p-(1-4)-β-D-2-乙酰氨基-2-脱氧葡萄糖-p-(1-的寡糖是腐生葡萄球菌对绵羊红细胞血凝作用的良好抑制剂。
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