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主动脉瓣人工瓣膜的体外壁面剪应力测量

In-vitro wall shear measurements at aortic valve prostheses.

作者信息

Tillmann W, Reul H, Herold M, Bruss K H, van Gilse J

出版信息

J Biomech. 1984;17(4):263-79. doi: 10.1016/0021-9290(84)90137-4.

Abstract

Wall shear distributions during the cardiac cycle at the valve rings of Starr-Edwards, Björk-Shiley and Lillehei-Kaster aortic valves are measured and compared with thresholds reported for shear-induced trauma of blood components. Further, for the disk valves, the influence of pulse rate on wall shear stresses is evaluated. Hot film anemometry with flush-mounted wall shear probes is used as measurement technique in a pulsatile flow mock circuit. The experimental systolic data support the better hemodynamic characteristics of the disk valves over the ball valve also with respect to the threshold shear stresses of flow induced blood trauma. These results are confirmed by postoperative clinical studies, where lower LDH-values are found with the disk than with the ball valves. During diastole, however, high shear stresses are measured and calculated at the valve ring of the Björk-Shiley prosthesis, which can be referred to the non-overlapping closing mechanism. This result is discussed with respect to the often observed thrombus formation at the disk downstream of the smaller orifice of the Björk-Shiley valve.

摘要

测量了Starr-Edwards、Björk-Shiley和Lillehei-Kaster主动脉瓣瓣环在心动周期中的壁面剪切力分布,并与报道的血液成分剪切诱导损伤阈值进行了比较。此外,对于盘状瓣膜,评估了脉搏率对壁面剪应力的影响。在脉动流模拟回路中,使用带有嵌入式壁面剪切探头的热膜风速仪作为测量技术。实验收缩期数据表明,就血流诱导血液损伤的阈值剪应力而言,盘状瓣膜的血流动力学特性也优于球瓣。术后临床研究证实了这些结果,其中发现使用盘状瓣膜时的乳酸脱氢酶值低于球瓣。然而,在舒张期,在Björk-Shiley人工瓣膜的瓣环处测量和计算到了高剪应力,这可能与非重叠关闭机制有关。针对Björk-Shiley瓣膜较小孔口下游盘片处经常观察到的血栓形成,对这一结果进行了讨论。

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