创伤性瘢痕疙瘩的多细胞起源
Multiple cell origin of traumatically induced keloids.
作者信息
Moulton-Levy P, Jackson C E, Levy H G, Fialkow P J
出版信息
J Am Acad Dermatol. 1984 Jun;10(6):986-8. doi: 10.1016/s0190-9622(84)80319-9.
PMID:6736343
Abstract
Six keloids from five patients heterozygous for the X-linked glucose-6-phosphate dehydrogenase (G6PD) locus were studied. Both the B and A enzymes were found in the keloids in similar proportions to the normal tissues. This finding indicates that keloids have a multicellular origin and that they do not develop clonally as do most neoplasms.
摘要
对5名X连锁葡萄糖-6-磷酸脱氢酶（G6PD）基因座杂合的患者的6个瘢痕疙瘩进行了研究。在瘢痕疙瘩中发现的B型和A型酶与正常组织中的比例相似。这一发现表明，瘢痕疙瘩具有多细胞起源，并且它们不像大多数肿瘤那样以克隆方式发展。
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