Overton J H
J Toxicol Environ Health. 1984;13(2-3):273-94. doi: 10.1080/15287398409530498.
The major physical and chemical processes involved in the transport and absorption of O3 or NO2 in the lower respiratory tract are discussed. This includes the development of respiratory tract models, flow patterns, and transport in tube networks, the mucous, surfactant, and tissue layers, and chemical reactions and transport of O3 or NO2 within these layers. Descriptions of the individual processes are simplified and integrated to illustrate the formulation of dosimetry models. Data from a dosimetry model, formulated from the concepts discussed, are used to illustrate the types of information obtained by modeling.
本文讨论了下呼吸道中臭氧（O3）或二氧化氮（NO2）传输与吸收所涉及的主要物理和化学过程。这包括呼吸道模型的建立、气流模式、管网中的传输、黏液、表面活性剂和组织层，以及这些层内O3或NO2的化学反应和传输。对各个过程的描述进行了简化和整合，以说明剂量学模型的构建。根据所讨论的概念建立的剂量学模型数据，用于说明通过建模获得的信息类型。
