Bouvet J P, Dechy H, Guilabert A, Levy R, Dorra M
Nouv Presse Med. 1978 Jun 3;7(22):1929-32.
The rheumatoid rosette test was performed in 33 patients with febrile valvular cardiopathy. In 19 cases bacterial endocarditis was proved by blood culture or by histological examination. The test was positive in 3 cases out of 5 during the first ten days of the fever (group A1), in 6 cases out of 6 after the tenth day (group A2), and in 4 out of the 8 already treated patients (group A3). In 3 positive cases, successive measurements, before and during treatment, showed a rapid fall in rosette levels. In controls patients, the test was positive 8 out of 9 cases with febrile valvular cardiopathy without endocarditis (group B) and in 5 out of 5 cases in which bacterial endocarditis was probable but not proved (group C). The increase in rheumatoid rosette levels seems therefore to be non specific of bacterial endocarditis. Nevertheless it could be a good test for biological activity of the disease in treated patients. The origin and signification of the rheumatoid rosette forming cells are discussed.
对33例发热性心脏瓣膜病患者进行了类风湿玫瑰花结试验。19例经血培养或组织学检查证实为细菌性心内膜炎。在发热的前十天，5例中有3例试验呈阳性（A1组），第十天后6例中有6例呈阳性（A2组），8例已治疗患者中有4例呈阳性（A3组）。在3例阳性病例中，治疗前和治疗期间的连续测量显示玫瑰花结水平迅速下降。在对照组中，9例无细菌性心内膜炎的发热性心脏瓣膜病患者中有8例试验呈阳性（B组），5例可能患有细菌性心内膜炎但未得到证实的患者中有5例呈阳性（C组）。因此，类风湿玫瑰花结水平的升高似乎并非细菌性心内膜炎所特有。然而，它可能是治疗患者疾病生物学活性的一个良好检测指标。文中讨论了类风湿玫瑰花结形成细胞的起源和意义。
