Najean Y, Pecking A, Le Mercier N, Zittoun R, Chaussade R
Nouv Presse Med. 1978 Jun 10;7(23):2027-30.
The sex, age, occupation and residence of 251 patients with aplastic anaemia in adults have been analyzed, and compared to those of the french population. The following observations have been done: excess of males at each age beyond the 20th year; excessive frequency after the 50th year; excessive frequency in the rural population and the inhabitants of villages and little towns; but no excess in the industrial workers. These observations lead to minimize the aetiological responsibility of industrial toxics in aplastic anaemia; at the reverse they invite to look for a possible responsibility of one or several agents used in the rural world.
对251例成人再生障碍性贫血患者的性别、年龄、职业和居住地进行了分析,并与法国人群的相应情况进行了比较。得出以下观察结果:20岁以后各年龄段男性均占多数;50岁以后发病率过高;农村人口以及村镇居民发病率过高;但产业工人中无此现象。这些观察结果使得再生障碍性贫血中工业毒物的病因学责任降至最低;相反,这促使人们去探寻农村环境中使用的一种或几种因素可能存在的责任。