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青少年滥用灭火剂与猝死

Abuse of a fire-extinguishing agent and sudden death in adolescents.

作者信息

Steadman C, Dorrington L C, Kay P, Stephens H

出版信息

Med J Aust. 1984 Jul 21;141(2):115-7.

PMID:6738424
Abstract

Two cases of abuse of bromochlorodifluoromethane (BCF - a fire-extinguishing agent) by inhalation are reported. In the first case, a 15-year-old youth presented in ventricular fibrillation; the second youth was dead on arrival at hospital. Port-mortem toxicological investigations confirmed BCF inhalation in the latter patient. Management of the surviving patient included cardioversion, controlled mandatory hyperventilation, intravenous infusions of mannitol, and barbiturate protection against cerebral ischaemia. He had completely recovered after eight days. Community agencies report that BCF inhalation occurs frequently on the Gold Coast, Queensland. This behaviour can be associated with sudden death from ventricular arrhythmias after cardiac sensitization to endogenous adrenaline. The "lone sniffer" is at greatest risk, and identification of such individuals may prevent a fatal outcome.

摘要

报告了两例吸入溴氯二氟甲烷(BCF,一种灭火剂)滥用的病例。第一例中,一名15岁青年出现心室颤动;第二例青年在抵达医院时已死亡。尸检毒理学调查证实后一名患者吸入了BCF。幸存患者的治疗包括心脏复律、控制性强制过度通气、静脉输注甘露醇以及使用巴比妥类药物预防脑缺血。八天后他已完全康复。社区机构报告称,在昆士兰州的黄金海岸,吸入BCF的情况经常发生。这种行为可能与心脏对内源性肾上腺素致敏后因室性心律失常导致的猝死有关。“独自嗅吸者”风险最大,识别出此类个体可能会避免致命后果。

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