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异常糖耐量(低血糖和高血糖)在子痫前期病因学中的重要性。

Importance of abnormal glucose tolerance (hypoglycaemia and hyperglycaemia) in the aetiology of pre-eclampsia.

作者信息

Long P A, Abell D A, Beischer N A

出版信息

Lancet. 1977 Apr 30;1(8018):923-5. doi: 10.1016/s0140-6736(77)92222-x.

DOI:10.1016/s0140-6736(77)92222-x
PMID:67385
Abstract

In a series of 794 patients who had glucose tolerance tests done before the onset of pre-eclampsia, both hypoglycaemia (less than 5th percentile) and hyperglycaemia (P less than 95th percentile) had a significant association with early-onset severe pre-eclampsia ( less than 0.05). In the total series of 794 patients, hypoglycaemia had a significant association with low oestriol excretion (p less than 0.01), fetal growth retardation (p less than 0-05), low Apgar score (p less than 0.05), and perinatal mortality (p less than 0.05). These data indicate that, in patients with pre-eclampsia, hypoglycaemia is directly related to the cause of perinatal death.

摘要

在一系列794例于子痫前期发作前进行葡萄糖耐量试验的患者中,低血糖(低于第5百分位数)和高血糖(P低于第95百分位数)均与早发型重度子痫前期显著相关(P<0.05)。在这794例患者的总体队列中,低血糖与雌三醇排泄量低(P<0.01)、胎儿生长受限(P<0.05)、阿氏评分低(P<0.05)及围产期死亡率(P<0.05)显著相关。这些数据表明,在子痫前期患者中,低血糖与围产期死亡原因直接相关。

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Importance of abnormal glucose tolerance (hypoglycaemia and hyperglycaemia) in the aetiology of pre-eclampsia.异常糖耐量(低血糖和高血糖)在子痫前期病因学中的重要性。
Lancet. 1977 Apr 30;1(8018):923-5. doi: 10.1016/s0140-6736(77)92222-x.
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The influence of abnormal glucose tolerance (hyperglycaemia and hypoglycaemia) on pregnancy outcome when oestriol excretion is subnormal.当雌三醇排泄量低于正常水平时,异常糖耐量(高血糖和低血糖)对妊娠结局的影响。
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