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[血管痣放疗后发生脑膜瘤。病例报告]

[Meningioma following irradiation for vascular nevus. A case report].

作者信息

Iwai T, Hattori T, Sakai N, Yamada H

出版信息

No Shinkei Geka. 1984 Mar;12(4):499-504.

PMID:6738796
Abstract

A case of meningioma that developed 37 years after irradiation therapy for vascular nevus of the scalp over the right frontoparietal region was reported. A 49-year-old male was admitted to the hospital of Gifu University on October 26, 1979, because of a generalized seizure. He had been born with a vascular nevus affecting the right frontoparietal scalp, for which he began receiving local irradiation at the age of 12. The total dose was not known because the only source of information regarding this treatment was the patient's memory. From the age of 17, the suffered from occasional attacks of dysesthesia in the left side of his body without consciousness disorder. He otherwise remained well for the intervening 37 years. Upon admission, he had a vascular nevus remaining with post irradiation skin changes over the right frontoparietal region. General and neurological examination were not remarkable. Right carotid angiogram and CT scan disclosed the presence of a right frontal tumor. A right frontotemporal craniotomy was performed on December 4, 1979 and a hard tumor was found firmly attached to the dura and bone at the right site. All visible tumor and involved bone were completely removed without difficulty. Histological examination of the surgical specimen showed the characteristic features of a transitional meningioma. There was no evidence of malignancy in the sections examined. Since Mann et al reported a malignant meningioma following irradiation therapy for optic nerve glioma, there have been many reports, over seventy cases of so-called radiation-induced meningioma. However, a meningioma following irradiation therapy for vascular nevus of scalp or face is exceedingly rare.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

报告了1例在右侧额顶部头皮血管痣接受放射治疗37年后发生的脑膜瘤。一名49岁男性于1979年10月26日因全身性癫痫发作入住岐阜大学医院。他出生时右侧额顶部头皮有血管痣,12岁开始接受局部放疗。由于关于该治疗的唯一信息来源是患者的记忆,所以总剂量不详。从17岁起,他偶尔出现左侧身体感觉异常发作,无意识障碍。在随后的37年里他身体状况良好。入院时,他右侧额顶部区域有血管痣残留及放疗后皮肤改变。全身及神经系统检查无明显异常。右侧颈动脉血管造影和CT扫描显示右侧额叶有肿瘤。1979年12月4日进行了右侧额颞开颅手术,发现一个硬肿瘤牢固附着于右侧部位的硬脑膜和骨。所有可见肿瘤及受累骨均顺利完全切除。手术标本的组织学检查显示为过渡型脑膜瘤的特征性表现。检查切片中无恶性证据。自从曼恩等人报告了视神经胶质瘤放射治疗后发生恶性脑膜瘤以来,已有许多报告,超过70例所谓的放射性诱导脑膜瘤。然而,头皮或面部血管痣放射治疗后发生脑膜瘤极为罕见。(摘要截短至250字)

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1
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