Knerich R, Butti G, Pezzotta S, Robustelli della Cuna G, Adinolfi D, Pavesi L
Minerva Med. 1984 Jun 8;75(24):1441-4.
The best conventional care for medulloblastoma and malignant ependymoma in children consists of surgery and radiotherapy. The preliminary observations of some authors suggested that chemotherapy could be useful in treating these tumors. The two major experiences in this field are those from SIOP and CCSG -RTOG trials which used chemotherapy as adjuvant to surgery and radiotherapy. In such studies chemotherapy appears to be effective mostly in high-risk patients. A study performed by Italian Child's Neurooncology Group ( ICNG ) confirms the preceding results.
儿童髓母细胞瘤和恶性室管膜瘤的最佳传统治疗方法包括手术和放疗。一些作者的初步观察表明，化疗可能对治疗这些肿瘤有用。该领域的两项主要经验来自SIOP和CCSG-RTOG试验，这些试验将化疗用作手术和放疗的辅助手段。在这类研究中，化疗似乎主要对高危患者有效。意大利儿童神经肿瘤学组（ICNG）进行的一项研究证实了上述结果。
