Deitz M R, Sanders D R, Marks R G
Ophthalmology. 1984 May;91(5):467-78. doi: 10.1016/s0161-6420(84)34264-6.
The first 290 consecutive eyes (192 patients) to undergo radial keratotomy by one surgeon were evaluated prospectively. All had had complete preoperative evaluation and 269 (93%) were examined one or more years after surgery. Preoperatively, all patients except one had worse than 20/100 uncorrected visual acuity, 65% had less than 20/400, and mean spherical equivalent (SE) was -4.8 diopters. One year postoperatively, 40% of the patients had uncorrected visual acuity of 20/20 or better and 83% had 20/40 or better. The mean change in SE after 1 year was 5.0 diopters, and 60% of eyes were within 1 diopter of emmetropia. Keratometric changes paralleled refractive changes, and both appeared stable within 1 to 3 months. Complications were few and most were transient or well-tolerated. One case of presumably viral disciform keratitis occurring 8 months postoperatively had a three Snellen line decrease in best-corrected acuity 1 year postoperatively. Factors affecting refractive outcome were studied using stepwise multiple regression analysis. Size of the optical zone, depth of incision, patient age, patient sex, intraocular pressure, number of incisions, preoperative average keratometry, and corneal diameter were each found to affect clinical outcome significantly.
对由一位外科医生实施放射状角膜切开术的连续290只眼(192例患者)进行了前瞻性评估。所有患者术前均接受了全面评估,术后1年或更长时间对其中269只眼(93%)进行了检查。术前,除1例患者外,所有患者的未矫正视力均低于20/100,65%的患者低于20/400,平均球镜当量(SE)为-4.8屈光度。术后1年,40%的患者未矫正视力达到20/20或更好,83%的患者达到20/40或更好。1年后SE的平均变化为5.0屈光度,60%的眼屈光不正度在正视眼的1屈光度范围内。角膜曲率计测量的变化与屈光变化平行,且在1至3个月内均趋于稳定。并发症较少,大多数为短暂性或耐受性良好。1例术后8个月发生的疑似病毒性盘状角膜炎患者,术后1年最佳矫正视力下降了三行Snellen视力表度数。使用逐步多元回归分析研究了影响屈光结果的因素。发现光学区大小、切口深度、患者年龄、患者性别、眼压、切口数量、术前平均角膜曲率和角膜直径均对临床结果有显著影响。