[Radiosensitizing and damaging action of hyperthermia on different biological systems. Radiosensitizing and damaging action of hyperthermia on mouse hematopoietic stem cells].

Dose dependences of heat-induced inactivation of CFUs have been described for the temperature range of 41 to 44 degrees C. The energy of activation of the processes of thermal death was 100-120 kcal/M. CFUs were more resistant to heating than the cells of mouse leukaemia. Heating 1 h or immediately before irradiation had a radiosensitizing effect on CFUs. When bone marrow cells were heated 1 h after irradiation the radiosensitizing effect was absent: there was only a simple summation of the effects of the two damaging agents.