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非洲爪蟾变态发育过程中视网膜神经节细胞层和视神经的形态计量学研究。

A morphometric study of the retinal ganglion cell layer and optic nerve from metamorphosis in Xenopus laevis.

作者信息

Dunlop S A, Beazley L D

出版信息

Vision Res. 1984;24(5):417-27. doi: 10.1016/0042-6989(84)90040-3.

DOI:10.1016/0042-6989(84)90040-3
PMID:6740963
Abstract

The number and distribution of cells in the retinal ganglion layer have been examined in Nissl-stained wholemounts during postmetamorphic life in Xenopus laevis. Total cell number at metamorphic climax, in the 3 and 4 month juveniles and in 5 year adults were 30,000-41,000, 45,000-51,000 and 71,000-82,000 respectively. Optic axon counts of 29,000, 39,000 and 58,000 at these stages suggested that most cells counted were ganglion cells and that their number doubled during this period. Cell distribution changed after metamorphosis producing nasal and temporal regions of higher density in juveniles and adults. These results are discussed in relation to retinal growth and plasticity of retinotectal connections.

摘要

在非洲爪蟾变态后的生命过程中,通过尼氏染色整装片对视网膜神经节层中的细胞数量和分布进行了检查。变态高峰期、3个月和4个月大的幼体以及5岁成体的细胞总数分别为30,000 - 41,000、45,000 - 51,000和71,000 - 82,000。在这些阶段,视神经轴突计数分别为29,000、39,000和58,000,这表明所计数的大多数细胞是神经节细胞,并且在此期间它们的数量增加了一倍。变态后细胞分布发生变化,在幼体和成体中产生了密度较高的鼻侧和颞侧区域。结合视网膜生长和视网膜 - 顶盖连接的可塑性对这些结果进行了讨论。

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