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[支气管肺疾病患儿支气管分泌物中糖皮质激素浓度测定的病理生理意义]

[Pathophysiological significance of the determination ofthe glucocorticoid concentration in bronchial secretions in children with bronchopulmonary diseases].

作者信息

Gavalov S M, Smirnova L P, Gizamulin Z Ia, Egunova S M, Muravleva G G

出版信息

Vopr Med Khim. 1984 Mar-Apr;30(2):37-40.

PMID:6740993
Abstract

Simultaneous estimation of glucocorticoid content was carried out in bronchial secretion products and in blood plasma of 95 children with chronic bronchopulmonary pathology. 11-hydroxycorticosteroids were found in bronchial secretion product; its concentration depended on the type, phase of the disease and the character of bronchial mucose impairment. The highest content of 11-hydroxycorticosteroids was observed in purulent endo-bronchitis.

摘要

对95名患有慢性支气管肺疾病的儿童的支气管分泌物和血浆中的糖皮质激素含量进行了同步测定。在支气管分泌物中发现了11-羟基皮质类固醇;其浓度取决于疾病的类型、阶段以及支气管黏膜损伤的特征。在脓性支气管炎中观察到11-羟基皮质类固醇的含量最高。

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