Vagner R I, Karaseva N A, Drukin E Ia
Vopr Onkol. 1984;30(6):53-7.
A correlation between the rate of growth of peripheral cancer of the lung and patient's age was established by a study involving 262 cases. The duration of tumor presence in the body appeared to be a factor influencing the process of tumor dissemination to regional lymph nodes. An analysis of the long-term results of surgical treatment of 127 patients yielded a significant correlation between the time of doubling of tumor size and survival within the first two years after operation. At later stages, survival rates tended to rise in patients with slowly-growing tumors, with the exception of those with the tumor doubling time under 20 days and a bad prognosis.
一项涉及262例病例的研究确定了肺外周癌的生长速率与患者年龄之间的相关性。肿瘤在体内存在的持续时间似乎是影响肿瘤扩散至区域淋巴结过程的一个因素。对127例患者手术治疗的长期结果进行分析发现，肿瘤大小倍增时间与术后头两年内的生存率之间存在显著相关性。在疾病后期，生长缓慢的肿瘤患者的生存率往往会上升，但肿瘤倍增时间在20天以下且预后不良的患者除外。
