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[体外电激活血液——一种用于阻断肿瘤供血动脉及肿瘤组织微循环的内源性致血栓形成物质——实验研究]

[In vitro electrically activated blood--an endogenous thrombogenic substance for the blocking of arteries supplying tumors and the microcirculation of tumor tissue--an experimental study].

作者信息

Sedlarik K M, Weidenbach H, Köhler H

出版信息

Z Urol Nephrol. 1984 Apr;77(4):193-9.

PMID:6741299
Abstract

Endovasal transcatheteral blockage of arteries supplying tumours is a clinically tested palliative measure and can also be used preoperatively to reduce intraoperative bleeding and the spread of tumour cells. In recent years several, mainly exogenic, substances have been used along with autologous muscle slurry and extracorporally produced autologous thromboses. Blood which has been exposed to the in-vitro effect of anodic direct current behaves like an endogenic thrombogenic substance. This can be used to block the microcirculation and the main artery of an organ, which results in its total dysfunction and loss of the parenchyma.

摘要

经血管内导管阻塞供应肿瘤的动脉是一种经过临床检验的姑息性措施,也可在术前使用以减少术中出血和肿瘤细胞扩散。近年来,除自体肌肉糊剂和体外产生的自体血栓外,还使用了几种主要为外源性的物质。暴露于阳极直流电体外效应的血液表现得像一种内源性血栓形成物质。这可用于阻塞器官的微循环和主要动脉,从而导致其完全功能障碍和实质丧失。

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