大麻与人类志愿者的情绪

Marihuana and mood in human volunteers.

作者信息

Rossi A M, Kuehnle J C, Mendelson J H

出版信息

Pharmacol Biochem Behav. 1978 Apr;8(4):447-53. doi: 10.1016/0091-3057(78)90084-9.

Abstract

Fifteen adult male marihuana smokers volunteered to live on a hospital research ward for a 31-day study which included a five-day baseline, a 21-day marihuana smoking period and a concluding five-day baseline. Subjects rated their moods and level of intoxication each day at scheduled occasions. Analyses of variance indicated a significant trend in the mood ratings which increased slightly in the euphoric direction just before smoking marihuana (compared to routine ratings) and further increased slightly after smoking marihuana. Level of intoxication ratings and mood ratings were not significantly correlated, but an intoxicated subject's mood ratings were significantly correlated with the average mood ratings of other subjects intoxicated or not. The results suggest that marihuana may increase a person's susceptibility to the moods of others and the feeling of being in harmony with others may be a positive reinforcer.

摘要

15名成年男性大麻吸食者自愿住进医院研究病房，参加一项为期31天的研究，该研究包括一个为期5天的基线期、一个为期21天的大麻吸食期以及最后一个为期5天的基线期。受试者在预定时间每天对自己的情绪和中毒程度进行评分。方差分析表明，情绪评分存在显著趋势，即在吸食大麻前（与常规评分相比）情绪评分朝着欣快感方向略有上升，吸食大麻后进一步略有上升。中毒程度评分与情绪评分无显著相关性，但中毒受试者的情绪评分与其他中毒或未中毒受试者的平均情绪评分显著相关。结果表明，大麻可能会增加一个人对他人情绪的敏感性，与他人和谐相处的感觉可能是一种积极强化因素。