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从同名现象估计近亲繁殖:与平均近亲繁殖系数的关系

The estimation of inbreeding from isonymy: relationship to the average inbreeding coefficient.

作者信息

Tay J S, Yip W C

出版信息

Ann Hum Genet. 1984 May;48(2):185-94. doi: 10.1111/j.1469-1809.1984.tb01013.x.

DOI:10.1111/j.1469-1809.1984.tb01013.x
PMID:6742778
Abstract

The inbreeding coefficient estimated by the isonymy method is often much larger than the average inbreeding coefficient (FD). One reason commonly stated is that the surnames are polyphyletic in origin in such cases. The purpose of this paper is to examine the relationship between the inbreeding calculated from isonymy and the average inbreeding coefficient. It was found that when the level of inbreeding is low, especially when the random isonymy (Pr) is much larger than FD, or when the number of surnames is small (which results in a larger value of Pr), isonymy tends to grossly overestimate FD. A small number of surnames per se (not necessarily due to polyphyletic origin of surnames) will be likely to result in an unduly high estimate of inbreeding. The equations established are illustrated by numerical examples.

摘要

通过姓氏相同法估计的近亲繁殖系数通常比平均近亲繁殖系数(FD)大得多。通常给出的一个原因是,在这种情况下姓氏起源具有多源性。本文的目的是研究根据姓氏相同法计算出的近亲繁殖与平均近亲繁殖系数之间的关系。研究发现,当近亲繁殖水平较低时,特别是当随机姓氏相同率(Pr)远大于FD时,或者当姓氏数量较少(这会导致Pr值较大)时,姓氏相同法往往会严重高估FD。姓氏数量少本身(不一定是由于姓氏起源具有多源性)可能会导致对近亲繁殖的估计过高。通过数值示例对所建立的方程进行了说明。

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