Hurtado L, Santomé J A, Fernández C, Cárdenas M
Arch Inst Cardiol Mex. 1984 Mar-Apr;54(2):121-9.
Cardiogenic shock is the most severe complication of acute myocardial infarction (AMI). The Acute Myocardial Infarction (AMI) complicated with shock has the highest mortality. Between january 1980 and june 1983, 903 patients with AMI were admitted to the CCU of the Instituto Nacional de Cardiolog ía; in 38 of them (4.2%) shock ensued. Of the patients with shock, 52.6% died soon after arrival and 25% died soon after shock developed. Only 10 patients could be controlled with a Swan-Ganz catheter and could be treated according to the hemodynamic features. Nine of them were males, the majority older than 60. Three of the 10, had a previous myocardial infarction, 4 had angina 1 arterial hypertension, and 1 diabetes. The AMI was anterior in five patients, diaphragmatic and lateral in one, diaphragmatic with right ventricular extension in two, lateral in one and antero septal in the last one. The clinical manifestations of angina persisted in 6. The shock state appeared in most of the cases during the first 6 hours. The PWP was higher than 18 mm Hg in all the patients. The cardiac index was less than 2, the systemic blood pressure under 90 mmHg and the peripheral resistance was elevated in all the cases. They were treated with digitalis, Dopamine and Sodium Nitroprusiate . Nine of the 10 patients died; five had post mortem examination. The coronary arteries were occluded with a recent thrombi and the necrosis involved more than 40.0% of the ventricular mass.(ABSTRACT TRUNCATED AT 250 WORDS)
心源性休克是急性心肌梗死(AMI)最严重的并发症。急性心肌梗死合并休克的死亡率最高。1980年1月至1983年6月,903例急性心肌梗死患者入住国家心脏病研究所冠心病监护病房;其中38例(4.2%)发生休克。休克患者中,52.6%在入院后不久死亡,25%在休克发生后不久死亡。只有10例患者可通过 Swan-Ganz 导管进行控制,并可根据血流动力学特征进行治疗。其中9例为男性,大多数年龄超过60岁。10例中有3例曾有过心肌梗死,4例有心绞痛、1例有动脉高血压,1例有糖尿病。5例急性心肌梗死发生在前壁,1例在膈面和侧壁,2例在膈面伴右心室扩展,1例在侧壁,最后1例在前间隔。6例患者心绞痛的临床表现持续存在。大多数病例的休克状态出现在最初6小时内。所有患者的肺毛细血管楔压(PWP)均高于18 mmHg。心脏指数均小于2,全身血压均低于90 mmHg,外周阻力均升高。他们接受了洋地黄、多巴胺和硝普钠治疗。10例患者中有9例死亡;5例进行了尸检。冠状动脉被近期血栓阻塞,坏死累及超过40.0%的心室肌质量。(摘要截选至250字)