Terrosu P, Ibba G V, Contini G M, Franceschino V
Br Heart J. 1984 Aug;52(2):154-63. doi: 10.1136/hrt.52.2.154.
The angiographic appearance of the coronary arteries during successful thrombolysis with urokinase was determined in 35 patients with acute myocardial infarction. The lysing process passed through several phases: (a) total coronary occlusion with a convex or irregular distal margin (phase 0); (b) increasing patency of the lumen (phase 1); (c) re-establishment of flow but with intraluminal filling defects and delayed distal flow possibly due to microemboli (phase 2); (d) partial or complete disappearance of the filling defects (phase 3); and (e) further widening of the lumen which eventually attains a smooth regular outline (phase 4). The angiographic features which indicate the presence of coronary thrombosis are occlusion with an irregular or scalloped margin, staining with contrast medium, and progressive patency of the occluded vessel showing intraluminal filling defects.
对35例急性心肌梗死患者在使用尿激酶成功溶栓期间冠状动脉的血管造影表现进行了测定。溶栓过程经历几个阶段：(a) 冠状动脉完全闭塞，远端边缘呈凸形或不规则形（0期）；(b) 管腔通畅性增加（1期）；(c) 血流重建，但管腔内有充盈缺损且远端血流延迟，可能是由于微栓子所致（2期）；(d) 充盈缺损部分或完全消失（3期）；(e) 管腔进一步增宽，最终呈现光滑规则的轮廓（4期）。提示冠状动脉血栓形成的血管造影特征为边缘不规则或呈扇形的闭塞、造影剂染色以及闭塞血管逐渐通畅伴管腔内充盈缺损。
