Abrams A, Braff D, Janowsky D, Hall S, Segal D
Pharmakopsychiatr Neuropsychopharmakol. 1978 Jul;11(4):177-9. doi: 10.1055/s-0028-1094576.
A case report of a catatonic patient is presented. Because of the similarity of catatonia to the animal behavior produced by intracerebral administration of beta-endorphin, an endogenous opioid, naloxone was administered. No effect was observed with naloxone, whereas both amobarbital and diazepam were able to reverse catatonic behavior. Testing of catatonic patients with naloxone may help further elucidate naloxone's reported anti-psychotic properties.
本文报告了一例紧张症患者的病例。由于紧张症与脑内注射内源性阿片类物质β-内啡肽所产生的动物行为相似，因此给予了纳洛酮。未观察到纳洛酮有任何效果，而戊巴比妥和地西泮均能够逆转紧张症行为。用纳洛酮对紧张症患者进行测试可能有助于进一步阐明纳洛酮所报道的抗精神病特性。
