Walsh T H, Mann C V
Br J Surg. 1984 Aug;71(8):597-9. doi: 10.1002/bjs.1800710810.
Forty-eight patients who presented to St. Mark's Hospital, London between 1948 and 1979 with smooth muscle neoplasms of the rectum or anal canal have been reviewed. Twenty-six tumours arose from the muscularis mucosae of the rectum. These lesions were small, asymptomatic and did not recur after local removal. Eighteen tumours arose from the muscularis externa of the rectum. Local excision of these resulted in a high local recurrence rate regardless of the degree of differentiation of the tumour but long-term survival figures were similar whether the tumours were treated by local or radical techniques. However, the prognosis did relate to the degree of tumour differentiation, being worst in the poorly differentiated group. In four cases the smooth muscle tumour arose from the internal sphincter of the anal canal.
对1948年至1979年间就诊于伦敦圣马克医院的48例直肠或肛管平滑肌肿瘤患者进行了回顾性研究。26例肿瘤起源于直肠黏膜肌层。这些病变较小，无症状，局部切除后未复发。18例肿瘤起源于直肠肌层外。无论肿瘤的分化程度如何，这些肿瘤的局部切除均导致较高的局部复发率，但无论采用局部治疗还是根治性治疗，长期生存率相似。然而，预后确实与肿瘤的分化程度有关，分化差的组预后最差。4例平滑肌肿瘤起源于肛管内括约肌。
