Cecchi F, Zuppiroli A, Favilli S, Di Bari M, Vannucci A, Pini R, Marchionni N
Clin Cardiol. 1984 Jul;7(7):405-12. doi: 10.1002/clc.4960070705.
In a series of 75 consecutive patients with transmural acute myocardial infarction (AMI) a right-to-left ventricular filling pressure ratio equal to or greater than 0.65 (RVFP/LVFP greater than or equal to 0.65) was assumed to be indicative of associated right ventricular infarction (RVI). Out of 45 patients with inferoposterior myocardial infarction, 11 (24%) had such hemodynamic evidence of right ventricular infarction (group A). The remaining 34 patients with inferoposterior myocardial infarction (group B) and the 30 patients with anterior myocardial infarction did not. Time-motion and two-dimensional echocardiographic examinations were performed 7-10 days after admission in the 62 patients who survived. Right ventricular wall asynergy was found in six of eight group A patients. In three of these, right ventricular dilatation was also present. No patient in group B with inferior infarction or with anterior infarction showed abnormal right ventricular wall motion. While hemodynamic monitoring seems presently the most specific diagnostic method and it is of invaluable help in the choice of the best pharmacological therapy of right ventricular failure due to RVI, two-dimensional echocardiography is probably highly sensitive and specific for the diagnosis of RVI, by detecting RV wall motion and thickening abnormalities. Due to advantages, such as noninvasivity and repeatibility, two-dimensional echocardiography can be used in the selection of patients who deserve hemodynamic monitoring and in follow-up studies.
在连续75例透壁性急性心肌梗死(AMI)患者中,右心室与左心室充盈压之比等于或大于0.65(RVFP/LVFP≥0.65)被认为提示合并右心室梗死(RVI)。在45例下后壁心肌梗死患者中,11例(24%)有右心室梗死的血流动力学证据(A组)。其余34例下后壁心肌梗死患者(B组)和30例前壁心肌梗死患者则没有。对62例存活患者在入院7 - 10天后进行了时间-运动和二维超声心动图检查。在A组的8例患者中有6例发现右心室壁运动不协调。其中3例还存在右心室扩张。B组中无论是下壁梗死患者还是前壁梗死患者均未显示右心室壁运动异常。虽然目前血流动力学监测似乎是最具特异性的诊断方法,且对因RVI导致的右心室衰竭选择最佳药物治疗非常有帮助,但二维超声心动图通过检测右心室壁运动和增厚异常,对RVI的诊断可能具有高度敏感性和特异性。由于具有无创性和可重复性等优点,二维超声心动图可用于选择值得进行血流动力学监测的患者以及随访研究。