Vicik G J, Mendiones M, Quinones C A, Thorne E G
Cutis. 1984 Jun;33(6):570-1.
Econazole nitrate 1.0 percent cream was compared with placebo for safety and efficacy in the treatment of 126 patients with tinea versicolor. Overall results showed that 97 percent of the patients who were treated with econazole nitrate 1.0 percent cream once a day achieved excellent or partial responses, while 62 percent of those patients applying the placebo cream attained similar responses. This difference is statistically significant (p = 0.001). The study results show that econazole nitrate cream is a valuable drug for the treatment of tinea versicolor.
将1%硝酸益康唑乳膏与安慰剂对照，评估其治疗126例花斑癣患者的安全性和有效性。总体结果显示，每天使用一次1%硝酸益康唑乳膏治疗的患者中，97%获得了显著或部分改善，而使用安慰剂乳膏的患者中这一比例为62%。两者差异具有统计学意义（p = 0.001）。研究结果表明，硝酸益康唑乳膏是治疗花斑癣的有效药物。
