Amacher A L, Wellington J
Childs Brain. 1984;11(4):217-29. doi: 10.1159/000120180.
A personal series of 170 children who underwent 636 operative procedures for hydrocephalus have been followed for 5-12 years. The results of treatment have been analyzed by etiology, years of follow-up, and summarized generally. 5-year survival was 83.5%, current survival is 78.8%. Normal intelligence was found in 63.4% of 5-year survivors, in 64.2% of current survivors. The procedural risk for early shunt infection was 5.8%, while 6.5% of the patients developed a late infection. There is no difference in results based upon measurement of the initial thickness of the cerebral mantle. The mean of the cumulative shunt procedures per patient is 3.72 +/- (SEM) 0.37, and for 5-year survivors it is 3.85 +/- (SEM) 0.39.
对一组共170名接受了636次脑积水手术的儿童进行了5至12年的随访。已根据病因、随访年限对治疗结果进行了分析,并进行了总体总结。5年生存率为83.5%,目前生存率为78.8%。在5年幸存者中,63.4%智力正常;在目前的幸存者中,64.2%智力正常。早期分流感染的手术风险为5.8%,而6.5%的患者发生了晚期感染。根据脑皮质初始厚度的测量结果,治疗效果没有差异。每名患者的分流手术累计平均数为3.72±(标准误)0.37,5年幸存者的这一数值为3.85±(标准误)0.39。