Elberger A J
Hum Neurobiol. 1984;3(2):115-20.
The corpus callosum and its role in the development of the cat visual system was studied in terms of the minimum group of intact callosal fibers needed for normal visual development to result. Additionally, the fate of these surviving callosal fibers was studied morphologically to determine whether the resulting pattern of connectivity could account for the subsequent visual development. Incomplete corpus callosum sections were made in cats within the first two postnatal weeks, a time period when a complete callosum section results in permanent visual deficits. Visual development was assessed as a function of visual acuity, and connectivity of the intact callosal fibers was defined using the retrograde tracer, horseradish peroxidase. The results indicate that only a portion of the visual corpus callosum fibers need to be intact during the critical period of corpus callosum development in order for normal callosal connectivity and a normal visual system to result.
从正常视觉发育所需的最小完整胼胝体纤维组的角度，对猫视觉系统发育过程中胼胝体及其作用进行了研究。此外，对这些存活的胼胝体纤维的命运进行了形态学研究，以确定由此产生的连接模式是否能够解释随后的视觉发育。在出生后的前两周内对猫进行不完全胼胝体切断，在此期间完全切断胼胝体会导致永久性视觉缺陷。视觉发育通过视敏度进行评估，完整胼胝体纤维的连接性使用逆行示踪剂辣根过氧化物酶进行定义。结果表明，在胼胝体发育的关键期，仅需一部分视觉胼胝体纤维保持完整，就能形成正常的胼胝体连接和正常的视觉系统。
