年轻和老年大鼠的睾丸血流及人绒毛膜促性腺激素的影响。

Testicular blood flow in young and old rats and influence of hCG.

作者信息

Punjabi U, van Hoecke J, Verdonck L, Vermeulen A

出版信息

J Androl. 1984 May-Jun;5(3):223-6. doi: 10.1002/j.1939-4640.1984.tb02400.x.

DOI:10.1002/j.1939-4640.1984.tb02400.x

Abstract

To evaluate the influence of age, testicular capillary blood flow (TCBF) was measured, using the microsphere technique, in rats 3 to 24 months old, under basal conditions and after hCG stimulation (10 IU/d for two days). Despite a decline in plasma T levels, testicular capillary blood flow did not decrease with age, and hCG stimulation resulted in similar increases of approximately 50% (P less than 0.01) in testicular capillary blood flow in all age groups. We concluded that the age-associated decrease in testosterone secretion in rats is not the consequence of a decreased testicular blood flow.

摘要

为评估年龄的影响，采用微球技术，在基础条件下以及人绒毛膜促性腺激素（hCG）刺激（10IU/天，持续两天）后，对3至24月龄大鼠的睾丸毛细血管血流量（TCBF）进行了测量。尽管血浆睾酮（T）水平下降，但睾丸毛细血管血流量并未随年龄增长而减少，且hCG刺激使所有年龄组的睾丸毛细血管血流量均增加了约50%（P<0.01）。我们得出结论，大鼠中与年龄相关的睾酮分泌减少并非睾丸血流量减少的结果。