Barbaro N M, Wilson C B, Gutin P H, Edwards M S
J Neurosurg. 1984 Sep;61(3):531-8. doi: 10.3171/jns.1984.61.3.0531.
The authors reviewed the clinical findings, radiological evaluation, and operative therapy of 39 patients with syringomyelia. Syringoperitoneal (SP) shunting was used in 15 patients and other procedures were used in 24 patients. Follow-up periods ranged from 1 1/2 to 12 years. During the period of this study, metrizamide myelography in conjunction with early and delayed computerized tomography scanning replaced all other diagnostic procedures in patients with syringomyelia. Preoperative accuracy for the two procedures was 87%. The most common symptoms were weakness (79%), sensory loss (67%), pain (38%), and leg stiffness (28%). Surgery was most effective in stabilizing or alleviating pain (100%), sensory loss (81%), and weakness (74%); spasticity, headache, and bowel or bladder dysfunction were less likely to be reversed. Approximately 80% of patients with idiopathic and posttraumatic syringomyelia and 70% of those with arachnoiditis improved or stabilized. Better results were obtained in patients with less severe neurological deficits, suggesting the need for early operative intervention. A higher percentage of patients had neurological improvement with SP shunting than with any other procedure, especially when SP shunting was the first operation performed. Patients treated with SP shunts also had the highest complication rate, most often shunt malfunction. These results indicate that SP shunting is effective in reversing or arresting neurological deterioration in patients with syringomyelia.
作者回顾了39例脊髓空洞症患者的临床症状、影像学评估及手术治疗情况。15例患者采用了脊髓空洞-腹腔(SP)分流术,24例患者采用了其他手术方式。随访时间为1.5年至12年。在本研究期间,脊髓造影联合早期及延迟计算机断层扫描取代了脊髓空洞症患者的所有其他诊断方法。这两种检查方法术前的准确率为87%。最常见的症状为肌无力(79%)、感觉丧失(67%)、疼痛(38%)和腿部僵硬(28%)。手术在稳定或缓解疼痛(100%)、感觉丧失(81%)和肌无力(74%)方面最为有效;痉挛、头痛以及肠道或膀胱功能障碍较难恢复。特发性和创伤后脊髓空洞症患者中约80%以及蛛网膜炎患者中70%的病情得到改善或稳定。神经功能缺损较轻的患者手术效果更佳,这表明需要早期进行手术干预。与其他任何手术方式相比,采用SP分流术的患者神经功能改善的比例更高,尤其是当SP分流术作为首次手术时。接受SP分流术治疗的患者并发症发生率也最高,最常见的是分流管故障。这些结果表明,SP分流术能有效逆转或阻止脊髓空洞症患者的神经功能恶化。