Hartman D A, Krier J
J Physiol. 1984 May;350:413-28. doi: 10.1113/jphysiol.1984.sp015209.
Intracellular recordings were obtained in vitro from two hundred and twenty post-ganglionic neurones of the fourth and fifth lumbar paravertebral ganglia of cats. Thirty-seven percent of neurones tested evoked antidromic responses during electrical stimulation of post-ganglionic fibres in the inferior lumbar splanchnic nerves. Twenty-seven percent of neurones tested evoked antidromic responses during electrical stimulation of post-ganglionic fibres in the lumbar sympathetic chain. Twenty-four percent of neurones tested evoked convergent antidromic responses during electrical stimulation of post-ganglionic fibres in separate inferior lumbar splanchnic nerves or lumbar sympathetic chain, and by inferior lumbar splanchnic nerves and lumbar sympathetic chain. Eighty-six percent of paravertebral post-ganglionic fibres which project to the inferior lumbar splanchnic nerves or lumbar sympathetic chain were composed of B fibres with maximal conduction velocities ranging from above 2.0 to 16.0 m/s. Fourteen percent of post-ganglionic fibres were composed of C fibres with maximal conduction velocities ranging from 0.2 to 2.0 m/s. Synaptic responses of neurones were recorded intracellularly during electrical stimulation of preganglionic fibres in inferior lumbar splanchnic nerves, lumbar white rami communicantes and lumbar sympathetic chain located one to three segments above the fourth and fifth lumbar ganglia and one to two segments below. Synaptic responses consisting of excitatory post-synaptic potentials and action potentials were mediated via nicotinic receptors. Twenty-seven percent of neurones tested received synaptic input from only one or two segments of the lumbar sympathetic chain. Seventy-three percent of neurones tested received convergent synaptic input from one or two segments of the lumbar sympathetic chain, lumbar white rami communicantes and inferior lumbar splanchnic nerves. It is concluded that central preganglionic fibres which project to inferior lumbar splanchnic nerves also project to the lumbar sympathetic chain to innervate neurones in the L4 and L5 ganglia. Synaptic responses of neurones during electrical stimulation of preganglionic fibres in the lumbar sympathetic chain and in the inferior lumbar splanchnic nerves were reduced in a chronic isolated segment of the sympathetic chain devoid of central preganglionic inputs. It is concluded that synaptic responses elicited in neurones during electrical stimulation of inferior lumbar splanchnic nerves and lumbar sympathetic chain were mediated in part via collaterals of central preganglionic axons and in part via axons whose cell bodies were located in the periphery.(ABSTRACT TRUNCATED AT 400 WORDS)
在体外对猫第四和第五腰旁神经节的220个节后神经元进行了细胞内记录。在电刺激腰内脏神经节后纤维时，37%的受试神经元诱发了逆向反应。在电刺激腰交感链节后纤维时，27%的受试神经元诱发了逆向反应。在分别电刺激腰内脏神经或腰交感链节后纤维以及同时电刺激腰内脏神经和腰交感链节后纤维时，24%的受试神经元诱发了会聚性逆向反应。投射至腰内脏神经或腰交感链的86%的腰旁节后纤维由B纤维组成，其最大传导速度在2.0至16.0米/秒之间。14%的节后纤维由C纤维组成，其最大传导速度在0.2至2.0米/秒之间。在电刺激位于第四和第五腰神经节上方一至三个节段以及下方一至两个节段的腰内脏神经、腰白交通支和腰交感链的节前纤维时，细胞内记录了神经元的突触反应。由兴奋性突触后电位和动作电位组成的突触反应是通过烟碱受体介导的。27%的受试神经元仅从腰交感链的一或两个节段接受突触输入。73%的受试神经元从腰交感链、腰白交通支和腰内脏神经的一或两个节段接受会聚性突触输入。得出的结论是，投射至腰内脏神经的中枢节前纤维也投射至腰交感链，以支配L4和L5神经节中的神经元。在缺乏中枢节前输入的慢性分离交感链节段中，电刺激腰交感链和腰内脏神经节前纤维时，神经元的突触反应减弱。得出的结论是，电刺激腰内脏神经和腰交感链时在神经元中引发的突触反应部分是通过中枢节前轴突的侧支介导的，部分是通过其细胞体位于外周的轴突介导的。（摘要截取自400字）
