Zhadin M N
J Theor Biol. 1984 Jun 21;108(4):565-95. doi: 10.1016/s0022-5193(84)80080-6.
A differential equation describing the electroencephalogram (EEG) is deduced based on the data on the structure of the brain cortex and the conceptions about a recurrent inhibition. This equation allows the study of a number of essential electrophysiological phenomena: the philogenetic differences in the frequency composition of the EEG, the shift of the EEG spectrum to higher frequencies upon excitation of the cortex, the lowering of the EEG rhythms and changes in cell reaction on deafferentation of the cortex, the identity in the spectra of a spontaneous EEG and evoked responses. A possible mechanism for the onset of epileptic activity is proposed.
基于大脑皮层结构数据和关于反馈抑制的概念,推导了一个描述脑电图(EEG)的微分方程。该方程有助于研究许多重要的电生理现象:EEG频率组成的种系发生差异、皮层兴奋时EEG频谱向更高频率的偏移、皮层去传入后EEG节律的降低以及细胞反应的变化、自发EEG和诱发反应频谱的一致性。提出了癫痫活动发作的一种可能机制。