Romatowski J
Mod Vet Pract. 1984 Jul;65(7):535-7.
A 9-year-old male German Shepherd had marked stumbling, staggering and weakness in both rear limbs. Pelvic radiographs revealed only mild hip dysplasia, while survey spinal radiographs and a myelogram revealed only areas of possible pachymeningitis. Results of CSF analysis were normal. Degenerative myelopathy was suspected, but a mitogen response assay failed to confirm this diagnosis. Another mitogen response assay, performed several months later, again failed to indicate degenerative myelopathy as the cause of clinical signs. The dog's condition worsened and the animal was euthanized. At necropsy, classic histopathologic lesions of degenerative myelopathy were noted in the thoracic spinal cord.
一只9岁的雄性德国牧羊犬后肢出现明显的蹒跚、摇晃和无力。骨盆X光片仅显示轻度髋关节发育不良，而脊柱X光片和脊髓造影仅显示可能存在硬脊膜炎的区域。脑脊液分析结果正常。怀疑患有退行性脊髓病，但有丝分裂原反应试验未能证实这一诊断。几个月后进行的另一次有丝分裂原反应试验也未能表明退行性脊髓病是临床症状的病因。这只狗的病情恶化，最终实施了安乐死。尸检时，在胸段脊髓发现了退行性脊髓病的典型组织病理学病变。
