以反复类白血病反应及持续性获得性粒细胞Pelger-Huët异常为前驱表现的原发性骨髓化生：病例报告并复习获得性Pelger-Huët异常

Agnogenic myeloid metaplasia preceded by repeated leukemoid reactions and persistent acquired Pelger-Huët anomaly of granulocytes: case report with review of acquired Pelger-Huët anomaly.

作者信息

O'Donnell J R, Farrell M A, Fitzgerald M X, O'Connell L G

出版信息

Cancer. 1982 Oct 15;50(8):1498-505. doi: 10.1002/1097-0142(19821015)50:8<1498::aid-cncr2820500809>3.0.co;2-2.

DOI:10.1002/1097-0142(19821015)50:8<1498::aid-cncr2820500809>3.0.co;2-2

Abstract

A case report of agnogenic myeloid metaplasia (AMM) is presented in which a patient had a preliminary 18-month period characterized by leukemoid reactions to repeated infections alternating with normal health, throughout which an acquired Pelger-Huët anomaly persisted. This is the only reported case of the anomaly as a premonitory hematologic marker of AMM. The literature concerning the acquired Pelger-Hut anomaly is reviewed.

摘要

本文报告了一例原发性骨髓化生（AMM）病例，该患者在最初的18个月里，反复感染引发类白血病反应与健康状态交替出现，在此期间获得性Pelger-Huët异常持续存在。这是唯一一例将该异常作为AMM先兆血液学标志物的报道病例。本文还对有关获得性Pelger-Huët异常的文献进行了综述。