Kurtz D, Krieger J
Rev Neurol (Paris). 1978 Jan;134(1):11-22.
The writers analyze 29 nyctohemeral recordings in 20 patients with sleep apneas. In addition to the standard polygraphy, use is made of pneumotachography and capnography. The results (central apnea with open or secondarily closed glottis; obstructive apnea with closed glottis or with expiratory valve phenomenon) raise the hypothesis of a central physiopathological mechanism common to the various types of apneas through a more or less dissociated inhibition of the activity of the respiratory, laryngeal, intercostal, and diaphragmatic muscles:--in central apnea: inhibition of the thoracoabdominal activity and maintenance of the tonicity of the laryngeal muscles, keeping the glottis open;--in obstructive apnea: persistence of the thoracic and/or abdominal activity with inhibition of the activity of the laryngeal muscles, leading to a passive obstruction due to the effect of inspiratory depression.
作者分析了20例睡眠呼吸暂停患者的29份昼夜记录。除了标准的多导睡眠图外,还使用了呼吸流速描记法和二氧化碳描记法。结果(中央型呼吸暂停伴声门开放或继发性关闭;阻塞型呼吸暂停伴声门关闭或有呼气瓣现象)通过对呼吸、喉部、肋间和膈肌活动或多或少的分离抑制,提出了各种类型呼吸暂停共同的中枢生理病理机制的假说:——在中央型呼吸暂停中:抑制胸腹活动并维持喉部肌肉的张力,使声门保持开放;——在阻塞型呼吸暂停中:胸和/或腹活动持续存在,同时抑制喉部肌肉活动,由于吸气抑制作用导致被动阻塞。