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[生长抑素用于急性溃疡出血的保守治疗。初步研究]

[Conservative therapy of acute ulcer hemorrhage using somatostatin. Pilot study].

作者信息

Kayasseh L, Gyr K, Stalder G A, Allgöwer M

出版信息

Schweiz Med Wochenschr. 1978 Jul 15;108(28):1083-4.

PMID:675201
Abstract

Somatostatin (SST) infusion was used to treat severe upper intestinal hemorrhage in 10 patients with peptic ulcer disease. Bleeding ceased in all patients 4-8 h after start of infusion. In one case bleeding recurred when SST infusion was discontinued; SST was given again and the hemorrhage definitively halted. Another patient suffered a recurrence while under SST infusion and had to be operated upon. SST appears to be effective in controlling hemorrhage from peptic ulcer, though further studies are required.

摘要

采用生长抑素(SST)静脉滴注治疗10例消化性溃疡病所致的严重上消化道出血。所有患者在开始滴注后4 - 8小时出血停止。1例在停止滴注SST后出血复发,再次给予SST后出血最终停止。另1例患者在SST滴注期间出血复发,不得不接受手术治疗。SST似乎对控制消化性溃疡出血有效,不过还需要进一步研究。

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