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足月胎鼠中枢神经系统膜中存在成人水平的胰岛素结合。

Adult-level insulin binding is present in term fetal rat CNS membranes.

作者信息

Kappy M S, Raizada M K

出版信息

Brain Res. 1982 Oct 14;249(2):390-2. doi: 10.1016/0006-8993(82)90075-0.

DOI:10.1016/0006-8993(82)90075-0
PMID:6754002
Abstract

Insulin binding was measured using partially-purified membranes prepared from the brains of term fetal and adult rats as the source of receptors. The membranes from the fetal rat brains bound at least as much insulin as did those from the adult rats at all concentrations of insulin used. This finding supports our hypothesis that insulin contributes to the postnatal growth of the rat brain.

摘要

使用从足月胎鼠和成年大鼠大脑制备的部分纯化膜作为受体来源来测量胰岛素结合情况。在所用的所有胰岛素浓度下,胎鼠大脑的膜与成年大鼠大脑的膜结合的胰岛素量至少一样多。这一发现支持了我们的假设,即胰岛素有助于大鼠大脑的出生后生长。

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Endocrine. 2001 Dec;16(3):227-34. doi: 10.1385/endo:16:3:227.
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