Hageman M J
Trop Geogr Med. 1978 Mar;30(1):45-55.
Waardenburg's syndrome is characterized by deafness and pigment disorders of the eyes, hair and skin. Two types are distinguished; e.g. type I with dystopia canthorum and type II without dystopia canthorum. In Kenya 12 out of 724 pupils of schoools for the deaf were found to suffer from the syndrome. Ten of these belonged to eight families; 20 other members of these families had signs of the syndrome. Of these 30 patients 18 had type I, 12 type II. The expression of most characteristics in these Kenyan patients was almost the same as in Caucasians. The mode of inheritance was autosomal dominant, as in Caucasians. The interocular distances were measured in 168 healthy children and adults of the Luo tribe. In most age groups slightly larger values were found than in the Caucasian race. For the diagnosis of dystopia canthorum this should be taken into account.
瓦登伯革氏综合征的特征是耳聋以及眼睛、头发和皮肤的色素紊乱。该病分为两种类型，例如，Ⅰ型伴有内眦异位，Ⅱ型不伴有内眦异位。在肯尼亚，724名聋哑学校学生中有12名被发现患有该综合征。其中10名来自8个家庭；这些家庭的另外20名成员有该综合征的体征。在这30名患者中，18名是Ⅰ型，12名是Ⅱ型。这些肯尼亚患者的大多数特征表现与高加索人几乎相同。遗传方式与高加索人一样，为常染色体显性遗传。对168名来自卢奥部落的健康儿童和成年人测量了两眼间距。在大多数年龄组中，发现两眼间距的值比高加索人种略大。在诊断内眦异位时应考虑到这一点。
