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[巨大皮肤角由全眶部皮肤移植处发展而来,并迅速演变为上皮瘤]

[Giant cutaneous horn developed at the expense of a total orbital skin graft and rapidly evolving into an epithelioma].

作者信息

Zolog N

出版信息

J Fr Ophtalmol. 1982;5(11):717-20.

PMID:6759564
Abstract

The author reports a patient who at the age of 4 years presented a tumour of the left internal canthus thus which after many extirpations presented as many times recurrences. An intense radiotherapy put an end to the recurrences at the cost of the atrophy of the left eye and of the destruction of the periocular tissues. After 25 years necrosis of these periocular tissues necessitated the exenteration of the left orbit followed by a free skin graft. 12 years later on the floor of the left orbit developed a giant cutaneous horn which was extirpated. After 4 months a similar tumour grew on the medial wall of the orbit which developed rapidly filling the orbit and invading the maxillary and ethmoidal sinuses. The histological examination of the tumour showed the characteristics of a squamous cell epithelioma. The author discusses further the possible role of the area on which was transplanted the skin, the role of the irradiation and finally of the scarce vascularization of the this orbit, in the tumoral proliferation.

摘要

作者报告了一名4岁时出现左内眦肿瘤的患者,该肿瘤经过多次切除后多次复发。强烈的放射治疗以左眼萎缩和眼周组织破坏为代价终止了复发。25年后,这些眼周组织坏死,需要进行左眼眶内容剜除术,随后进行游离皮肤移植。12年后,左眼眶底部长出一个巨大的皮角并被切除。4个月后,眼眶内侧壁长出一个类似的肿瘤,迅速生长,填满眼眶并侵犯上颌窦和筛窦。肿瘤的组织学检查显示为鳞状细胞上皮瘤的特征。作者进一步讨论了移植皮肤的区域、放射治疗以及该眼眶血管化不足在肿瘤增殖中可能发挥的作用。

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