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[皮肤病学中的维甲酸类药物]

[Retinoids in dermatology].

作者信息

De Moragas J M

出版信息

Med Cutan Ibero Lat Am. 1982;10(3):165-76.

PMID:6759810
Abstract

The Vitamin A. derivatives known as Retinoids, are among the most exciting pharmacological agents used in the last few years. They strongly influence the keratinizing epithelia, have an antipromoting effect upon experimentally induced tumors and have immunomodulatory activities. Teratogenicity seems to be the most worrisome effect of the retinoids. However, it is reasonable to assume their release for physicians prescription in the near future. This review is intended to provide a general background for their correct use by dermatologists.

摘要

被称为类视黄醇的维生素A衍生物,是过去几年中使用的最令人兴奋的药物之一。它们对角化上皮有强烈影响,对实验诱导的肿瘤有抗促进作用,并具有免疫调节活性。致畸性似乎是类视黄醇最令人担忧的影响。然而,有理由认为在不久的将来它们会被允许用于医生处方。这篇综述旨在为皮肤科医生正确使用它们提供一个总体背景。

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