从马恩岛牛的血液中分离出嗜吞噬细胞无形体的一种强毒株。
Isolation of a virulent strain of Ehrlichia phagocytophila from the blood of cattle in the Isle of Man.
作者信息
Purnell R E, Brocklesby D W
出版信息
Vet Rec. 1978 Jun 24;102(25):552-3. doi: 10.1136/vr.102.25.552.
PMID:676008
Abstract
A blood sample from a cow in the Isle of Man caused a severe Ehrlichia phagocytophila infection when inoculated into a splenectomised calf. The parasite was passaged successively into a further splenectomised calf and then into two intact animals. One of the splenectomised calves and one of the intact animals died of the infection which was characterised by causing a sustained febrile response apparently correlated with a marked invasion of monocytes by the rickettsiae.
摘要
从马恩岛一头奶牛采集的血样接种到一只脾切除的小牛体内后，引发了严重的嗜吞噬细胞无形体感染。该寄生虫先后在另一只脾切除的小牛以及两只未切除脾脏的动物体内传代。其中一只脾切除的小牛和一只未切除脾脏的动物死于该感染，其特征为引发持续发热反应，这显然与立克次氏体对单核细胞的显著侵袭有关。
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