Khavin I B
Probl Endokrinol (Mosk). 1982 Nov-Dec;28(6):7-11.
Diabetes mellitus predisposition is observed in the increased insulin activity of the pancreatic islet, followed by its exhaustion, and in its congenital or postnatal decreased activity. The former is seen in obese subjects, in large-born children and their mothers or in the children, whose mothers suffered from diabetes mellitus during pregnancy. The latter is discovered in hereditary diabetes mellitus, in hypertension and angiosclerosis. To avert diabetes mellitus in predisposed subjects a fixed-calory diet should be recommended for the pancreatic islet protection. Systematic blood and urine examinations are to be performed for revealing the initial pancreatic islet damage. Prophylactic treatment of these patients is realized by endocrinologists and the selection for therapy is carried out by special physicians.
在胰岛胰岛素活性增加随后出现衰竭以及先天性或出生后胰岛素活性降低的情况下，可观察到糖尿病易感性。前者见于肥胖者、出生体重较大的儿童及其母亲，或其母亲在孕期患糖尿病的儿童。后者见于遗传性糖尿病、高血压和血管硬化。为避免易感人群患糖尿病，应建议采用固定热量饮食以保护胰岛。应定期进行血液和尿液检查以发现胰岛的早期损伤。这些患者的预防性治疗由内分泌科医生实施，治疗方案的选择由专科医生进行。
