[Large-scale structural changes of yeast phosphoglycerate kinase molecule upon substrate binding].

Changes of dimensions and form of the yeast phosphoglyceratekinase molecule upon ATP and 3-phosphoglycerate binding have been investigated by diffuse X-ray scattering. It has been shown that simultaneous sorption of both substrates is accompanied by an essential decrease both of the radius of gyration and the extent of asymmetry of the phosphoglyceratekinase molecule.