Seo M L, Inouye M, Kiyono S, Shibagaki M
Teratology. 1982 Dec;26(3):221-7. doi: 10.1002/tera.1420260302.
Pregnant rats received 100 rads of X-irradiation on day 17 of gestation. Control pregnant rats were sham-irradiated on the same gestation day. The male offspring were reared under environmentally enriched, standard colony, and impoverished conditions for 30 days after weaning. Then the Hebb-Williams maze test was carried out. All the prenatally X-irradiated rats were microcephalic: their mean cerebral wet weight was 15.5% less than controls. The effect of X-irradiation was not significant in error scores and running times, whereas the effect of environment was significant in these items; initial and total error scores and running times were decreased in enriched groups compared to impoverished groups in controls as well as in X-irradiated animals.
怀孕大鼠在妊娠第17天接受100拉德的X射线照射。对照怀孕大鼠在相同妊娠日接受假照射。雄性后代在断奶后分别在环境丰富、标准饲养和贫乏条件下饲养30天。然后进行赫布 - 威廉姆斯迷宫试验。所有产前接受X射线照射的大鼠均为小头畸形：其平均脑湿重比对照组低15.5%。X射线照射对错误分数和奔跑时间的影响不显著，而环境对这些指标的影响显著；与对照组和接受X射线照射的动物的贫乏组相比，丰富组的初始和总错误分数以及奔跑时间均降低。
