Sudik R, Wilken H
Zentralbl Gynakol. 1982;104(17):1057-71.
An account is given of present applications of interceptively acting substances. Pharmaceuticals used so far for postcoital conception (oestrogens, gestagens, and combinations of these) are suitable for single application, but their regular use is limited by side-effects. Various approaches are being taken to the development of effective interceptives for high-continuity application but with low side-effects. Antigestagens, LHRH-analogues, and immunological contraceptives seem to be among the most promising classes of substances for the above purpose. Yet, none of these substances has been developed as yet to the level of clinical applicability.
本文介绍了具有阻断作用物质的当前应用情况。迄今为止用于性交后避孕的药物(雌激素、孕激素及其组合)适合单次使用,但其常规使用受到副作用的限制。目前正在采取各种方法来开发高效且副作用小的长效阻断剂。抗孕激素、促性腺激素释放激素类似物和免疫避孕药物似乎是最有希望用于上述目的的几类物质。然而,这些物质目前均未发展到临床可应用的水平。