Egger H, Weigmann P
Arch Gynecol. 1982;233(1):37-45. doi: 10.1007/BF02110677.
The case histories of 263 patients with histologically proven endometriotic cysts of the ovaries (1962-1979) were studied. The diagnosis frequency increased continuously during the observation period. Most patients were aged 35-39 years. The admission diagnosis was rarely endometriosis. The clinical picture and the extent of the disease rarely showed correlation. At laparotomy 12% of the chocolate cysts had ruptured spontaneously (31 of 263) and half of the cysts ruptured during surgery without adverse effects on the postoperative course. The recurrence rate in patients treated by conservative surgery was 7%. The most frequent accompanying diseases were uterine fibroids (42%) and adenomyosis (42%). One third of the patients presented with bilateral endometriotic cysts. Further foci of endometriosis tissue were frequently found in the affected ovary (55%) and in the other pelvic organs (43%). Only 4% of the ipsilateral oviducts were closed at their fimbrial end, and only 10% showed signs of endosalpingitis. The incidence of infection in endometriotic cysts--formation of an isolated ovarian abscess--was between 8% and 18%, while the risk of carcinoma was less than 1%.
对263例经组织学证实为卵巢子宫内膜异位囊肿患者(1962 - 1979年)的病历进行了研究。在观察期间,诊断频率持续增加。大多数患者年龄在35 - 39岁。入院诊断很少是子宫内膜异位症。临床表现与疾病程度之间很少显示出相关性。在剖腹手术中,12%的巧克力囊肿(263例中的31例)已自发破裂,并且一半的囊肿在手术期间破裂,对术后病程无不良影响。接受保守手术治疗的患者复发率为7%。最常见的伴随疾病是子宫肌瘤(42%)和子宫腺肌病(42%)。三分之一的患者出现双侧子宫内膜异位囊肿。在受影响的卵巢中经常发现子宫内膜异位组织的其他病灶(55%),在其他盆腔器官中也有发现(43%)。同侧输卵管伞端闭合的仅占4%,仅有10%显示输卵管内膜炎的迹象。子宫内膜异位囊肿中感染(形成孤立性卵巢脓肿)的发生率在8%至18%之间,而癌变风险小于1%。