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新型利尿剂托拉塞米治疗急性心力衰竭患者的临床疗效:与呋塞米的双盲对照研究

Clinical efficacy of torasemide, a new diuretic agent, in patients with acute heart failure: a double blind comparison with furosemide.

作者信息

Stroobandt R, Dodion L, Kesteloot H

出版信息

Arch Int Pharmacodyn Ther. 1982 Nov;260(1):151-8.

PMID:6762167
Abstract

Torasemide 60 mg and furosemide 120 mg were administered intravenously in a randomized double blind study in twelve patients with acute heart failure. The action of both drugs on urinary electrolyte and water excretion was very similar. The administration of torasemide but not of furosemide resulted in a significant reduction of systolic and diastolic blood pressure. No side effects occurred with either of the drugs in this elderly patient group.

摘要

在一项针对12例急性心力衰竭患者的随机双盲研究中,静脉注射了60毫克托拉塞米和120毫克呋塞米。两种药物对尿电解质和水排泄的作用非常相似。托拉塞米的给药导致收缩压和舒张压显著降低,而呋塞米则未出现这种情况。在这个老年患者组中,两种药物均未产生副作用。

相似文献

1
Clinical efficacy of torasemide, a new diuretic agent, in patients with acute heart failure: a double blind comparison with furosemide.新型利尿剂托拉塞米治疗急性心力衰竭患者的临床疗效:与呋塞米的双盲对照研究
Arch Int Pharmacodyn Ther. 1982 Nov;260(1):151-8.
2
Single dose comparison of torasemide and furosemide in patients with advanced renal failure.
Arzneimittelforschung. 1988 Jan;38(1A):200-4.
3
Comparison of efficacy and tolerance of different oral doses of torasemide and furosemide in patients with advanced chronic renal failure.不同口服剂量托拉塞米和呋塞米对晚期慢性肾衰竭患者疗效及耐受性的比较
Arzneimittelforschung. 1988 Jan;38(1A):212-4.
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Comparative pharmacodynamics of torasemide and furosemide in patients with oedema.托拉塞米与呋塞米对水肿患者的药效学比较
Arzneimittelforschung. 1988 Jan;38(1A):180-3.
5
Dose-dependent salidiuretic efficacy of torasemide in comparison to furosemide and placebo in advanced renal failure.
Arzneimittelforschung. 1988 Jan;38(1A):205-8.
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Diuretic activity of torasemide and furosemide in chronic heart failure: a comparative double blind cross-over study.托拉塞米和呋塞米在慢性心力衰竭中的利尿活性:一项比较性双盲交叉研究。
Eur J Clin Pharmacol. 1986;31 Suppl:35-42. doi: 10.1007/BF00541465.
7
[Torasemide (LUPRAC): a review of its pharmacological and clinical profile].[托拉塞米(鲁普拉克):其药理和临床概况综述]
Nihon Yakurigaku Zasshi. 2001 Aug;118(2):97-105. doi: 10.1254/fpj.118.97.
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Torasemide, a new potent diuretic. Double-blind comparison with furosemide.托拉塞米,一种新型强效利尿剂。与呋塞米的双盲对照研究。
Eur J Clin Pharmacol. 1986;31 Suppl:29-34. doi: 10.1007/BF00541464.
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Comparison of the effects of torasemide and furosemide in nonazotemic cirrhotic patients with ascites: a randomized, double-blind study.托拉塞米与呋塞米对非氮质血症肝硬化腹水患者疗效的比较:一项随机双盲研究。
Hepatology. 1991 Jun;13(6):1101-5.
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[Long-term diuretic treatment in heart failure: are there differences between furosemide and torasemide?].[心力衰竭的长期利尿治疗:呋塞米和托拉塞米之间有差异吗?]
Praxis (Bern 1994). 2002 Sep 11;91(37):1467-75. doi: 10.1024/0369-8394.91.37.1467.

引用本文的文献

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Comparative analysis of furosemide and torsemide efficacy in 24 hours of acute heart failure admission.急性心力衰竭入院24小时内呋塞米与托拉塞米疗效的对比分析
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Diuretics: a review of the pharmacology and effects on glucose homeostasis.利尿剂:药理学及其对葡萄糖稳态影响的综述
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Mechanistic Differences between Torsemide and Furosemide.托拉塞米和呋塞米之间的作用机制差异。
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Comparative effects of furosemide and other diuretics in the treatment of heart failure: a systematic review and combined meta-analysis of randomized controlled trials.速尿和其他利尿剂治疗心力衰竭的比较效果:系统评价和随机对照试验的联合荟萃分析。
Heart Fail Rev. 2021 Jan;26(1):127-136. doi: 10.1007/s10741-020-10003-7.
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Serelaxin for the treatment of acute heart failure: a review with a focus on end-organ protection.Serelaxin 治疗急性心力衰竭:关注终末器官保护的综述。
Eur Heart J Cardiovasc Pharmacother. 2016 Apr;2(2):119-30. doi: 10.1093/ehjcvp/pvv046. Epub 2015 Nov 26.
6
Optimal use of diuretics in patients with heart failure.
Curr Treat Options Cardiovasc Med. 2007 Aug;9(4):332-42. doi: 10.1007/s11936-007-0028-z.
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Torasemide: a pharmacoeconomic review of its use in chronic heart failure.托拉塞米:对其用于慢性心力衰竭的药物经济学综述
Pharmacoeconomics. 2001;19(6):679-703. doi: 10.2165/00019053-200119060-00006.
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Benefits and risks of torasemide in congestive heart failure and essential hypertension.托拉塞米在充血性心力衰竭和原发性高血压中的益处与风险。
Drug Saf. 1996 Feb;14(2):104-20. doi: 10.2165/00002018-199614020-00005.
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Torasemide. An update of its pharmacological properties and therapeutic efficacy.托拉塞米。其药理特性与治疗效果的最新进展。
Drugs. 1995 Jan;49(1):121-42. doi: 10.2165/00003495-199549010-00009.
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The efficacy of diuretics in acute and chronic renal failure. Focus on torasemide.利尿剂在急性和慢性肾衰竭中的疗效。重点关注托拉塞米。
Drugs. 1991;41 Suppl 3:69-79. doi: 10.2165/00003495-199100413-00008.