Stroobandt R, Dodion L, Kesteloot H
Arch Int Pharmacodyn Ther. 1982 Nov;260(1):151-8.
Torasemide 60 mg and furosemide 120 mg were administered intravenously in a randomized double blind study in twelve patients with acute heart failure. The action of both drugs on urinary electrolyte and water excretion was very similar. The administration of torasemide but not of furosemide resulted in a significant reduction of systolic and diastolic blood pressure. No side effects occurred with either of the drugs in this elderly patient group.
在一项针对12例急性心力衰竭患者的随机双盲研究中,静脉注射了60毫克托拉塞米和120毫克呋塞米。两种药物对尿电解质和水排泄的作用非常相似。托拉塞米的给药导致收缩压和舒张压显著降低,而呋塞米则未出现这种情况。在这个老年患者组中,两种药物均未产生副作用。