Boranic M, Poljak-Blazi M, Pericic D, Manev H
Biomed Pharmacother. 1982;36(4):203-5.
Rats were immunized with sheep erythrocytes, and 4 days in succession were stressed by restraint for 3 hours/day, or injected with dextro-amphetamine (7.5 mg/kg/day) or propranolol (0.1 mg/kg/day), or both stressed and treated with one of the drugs. Hemolytic plaque-forming cells (PFC) were counted in the spleens on the 5th day. Stress caused marginal suppression of the PFC response. The suppression was considerably potentiated by amphetamine and negligibly so by propranolol. Effect of the drugs has been discussed in view of altered corticosterone secretion.
用绵羊红细胞对大鼠进行免疫，连续4天每天约束应激3小时，或注射右旋苯丙胺（7.5毫克/千克/天）或普萘洛尔（0.1毫克/千克/天），或既进行应激又用其中一种药物处理。在第5天对脾脏中的溶血空斑形成细胞（PFC）进行计数。应激导致PFC反应出现轻微抑制。苯丙胺可显著增强这种抑制作用，而普萘洛尔的增强作用可忽略不计。根据皮质酮分泌的变化对药物的作用进行了讨论。
